Project No.1
I.Name of project
Biological Engineering Center of Industrial Company Group of
Yanshan University
2.Content of project
Biological pharmacy and the related industries are regarded as
the frontier subject of this century and will have revolutionary
influence on the traditional way of the making of drugs and
medicines. Owing to the successful proceeding of the global human
genenome plan and the never ending changes and improvement
of molecular biology technologies, biological pharmacy will become
the newest, quickest and most economic method used in the future
pharmaceutical industry.
Rt-PA ,the product of this project, is produced from the
mutation of t-PA by the use of genetic engineering technologies.
This technological product overcomes the drawbacks of some
existent thrombolytic medicine, which are present in may aspects
such as production of antibody after the medicine is taken ,short
half life, easy formation of general lytic state and great side ¨Ceffect,
etc. Moreover ,its throm bolytic effect is much better than that of
traditional thrombolytic medicines that it can remove thrombus in
the blocked blood vessel as soon as possible and reduce the death
rate greatly.
3.Investment Estimation
The total investment of this project is USD15 million, of which
USD 3.5 million is devoted to capital construction, USD 7.3 million
to the purchase of equipment ,USD 3.7 million to circulating funds
and 0.5 million to other .Of the investment ,foreign capital amounts
to USD 10 million
4.Market Analysis
Thrombolytic medicines which are allowed to be used in clinic
practice at present are scarce and mostly imported at a fairly high
price.The main thrombolytic medicines include rt-Pa ,streptokinase
and urokinase,etc., but only urokinase can be made in China ¨Cin
small amount. And its quality and quantity both fail to meet the clini
demand. At present the price of the imported rt-PA is RMB 8000 a
dosage. In view of the fact that there are 1.1 million of people in our
country each year who suffer from the acute myocardinal infraction ,
even if only 10 percent of these patients take the thrombolytic
medicine developed by us ,there will be a demand of 0.11 million of
dosages, which will bring us in RMB 0.33 billion worth of sales
income.
Thus it can be clearly seen that research and development of
mass RT-PA of high quality and at proper price can not only relieve
individual and national burden and save lots of foreign exchange,
but also bring about great economic benefits.
5.Conditions for construction
The new production base is located in Zone in Qinhuangdao
Economic and Technological Development Zone. The zone is well-
equipped with fundamental facilities and neither the three
wastes(waste gas, waste water and industrial residue)nor any other
pollution source is found around its peripheral zones. What's more,
the transportation by road, rail and sea is very convenient. Three
main railway lines cross here, and two national highways and one
motorway pass through the two sits of it. Since it is only 1.5
kilometer away from Qinhuangdao harbor, containers can be put on
board and trasnported directly to HongKong, Japan and South
Korea or transshipped to the North America and Western Europe
via HongKong.
The main raw material for this project is available in the
domestic market.
6.Economic Benefit Analysis
The construction period of this project is one year. It will bring
in USD 20 million worth of annual sales income and USD 6.3
million worth of annual profits .And the profit margin of the
investment will be 42 percent and the internal earning ratio be 29
percent. All the investment will return in three years.
7.Present Conditions of the Local Conpany
Industry Company Group of Yanshan University is the first
industrial company group in Hebei province which is founded by
colleges and universities. After ten years of hard pioneer work and
unceasing development, the company, supported by high-tech, has
expanded into an industrial company group which has a total staff
of 300 and 11 subordinate companies. The total assets of the
company is approximately RMB 300 million ,and its main products
cover a wide range, including automobile accessories
electromachanical, equipment, computer software products and
drill bits etc.. Now the company is striding forward towards fiber-
optical and fine electronnic industies. In 1998 the company made
an output value of RMB 80 million and a profit of more than RMB
10 million. Since 1996 the econmic indicators of the company have
been ranking first among industrial companies run by colleges and
universities which are affiliated to the Ministry of Machinery and
Hebei Province. The high-tech Garden of Yanshan University,which
has been formally listed as the key project in Hebei province and
the 1999 NO.1 project in Qinhuangdao city ,was founded by
Industrial Company Group of Yanshan University at the end of
1998.It is estimated that the total investment will be RMB 250
million ,and the annual output value be RMB 250 million, and the
sales profit be RMB 100 million.
8.Contact:
Person to contact:Zhangli
Unit: Industrial company Group of Yanshan University
Add:NO.438,western Hebei street,Qinhuangdao ,Hebei, China
Tel:0086-335-8057093
Fax:0086-335-8051847
E-mail:Gaoming@ysu.edu.cn
Post code:066004
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